All Phenotypes Fkbp5<tm1Dvds> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Fkbp5^tm1Dvds
targeted mutation 1, David F Smith
MGI:5296970

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fkbp5^tm1Dvds/Fkbp5^tm1Dvds	involves: 129X1/SvJ	MGI:5296972
hm2	Fkbp5^tm1Dvds/Fkbp5^tm1Dvds	involves: 129X1/SvJ * C57BL/6 * Swiss Webster	MGI:5297050

Allelic Composition	Fkbp5^tm1Dvds/Fkbp5^tm1Dvds
Genetic Background	involves: 129X1/SvJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fkbp5^tm1Dvds mutation (2 available); any Fkbp5 mutation (170 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

reproductive system phenotype ( J:101405 )

N	• mice exhibit normal fertility

Allelic Composition	Fkbp5^tm1Dvds/Fkbp5^tm1Dvds
Genetic Background	involves: 129X1/SvJ * C57BL/6 * Swiss Webster

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fkbp5^tm1Dvds mutation (2 available); any Fkbp5 mutation (170 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:177683 )

N	• mice exhibit normal locomotor activity, motor coordination, learning, memory, prepulse inhibition, conditioning, and startle response

• in a forced swim test and tail suspension test, mice spend less time immobilized compared with wild-type mice

• mice exhibit a non-significant increase in anxiety with age unlike wild-type mice

homeostasis/metabolism

• in stressed mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24