All Phenotypes Fkbp5<tm1Dvds> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Fkbp5^tm1Dvds
targeted mutation 1, David F Smith
MGI:5296970

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fkbp5^tm1Dvds/Fkbp5^tm1Dvds	involves: 129X1/SvJ	MGI:5296972
hm2	Fkbp5^tm1Dvds/Fkbp5^tm1Dvds	involves: 129X1/SvJ * C57BL/6 * Swiss Webster	MGI:5297050

Allelic Composition	Fkbp5^tm1Dvds/Fkbp5^tm1Dvds
Genetic Background	involves: 129X1/SvJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fkbp5^tm1Dvds mutation (2 available); any Fkbp5 mutation (170 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

reproductive system phenotype ( J:101405 )

N	• mice exhibit normal fertility

Allelic Composition	Fkbp5^tm1Dvds/Fkbp5^tm1Dvds
Genetic Background	involves: 129X1/SvJ * C57BL/6 * Swiss Webster

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fkbp5^tm1Dvds mutation (2 available); any Fkbp5 mutation (170 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:177683 )

N	• mice exhibit normal locomotor activity, motor coordination, learning, memory, prepulse inhibition, conditioning, and startle response

• in a forced swim test and tail suspension test, mice spend less time immobilized compared with wild-type mice

• mice exhibit a non-significant increase in anxiety with age unlike wild-type mice

homeostasis/metabolism

• in stressed mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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