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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Gab2tm4.1Thir
targeted mutation 4.1, Toshio Hirano
MGI:5297248
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Gab2tm4.1Thir/Gab2tm4.1Thir involves: 129T/SvJcl * C57BL/6Jcl MGI:5297353


Genotype
MGI:5297353
hm1
Allelic
Composition
Gab2tm4.1Thir/Gab2tm4.1Thir
Genetic
Background
involves: 129T/SvJcl * C57BL/6Jcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gab2tm4.1Thir mutation (1 available); any Gab2 mutation (37 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
N
• bone marrow-derived mast cells exhibit normal Fcer1-induced cytokine production
• in mucosal mast cells, but not skin mast cells

hematopoietic system
• in mucosal mast cells, but not skin mast cells

cellular





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory