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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cd247m1Btlr
mutation 1, Bruce Beutler
MGI:5297360
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Cd247m1Btlr/Cd247m1Btlr C57BL/6J-Cd247m1Btlr MGI:5297490


Genotype
MGI:5297490
hm1
Allelic
Composition		 Cd247m1Btlr/Cd247m1Btlr
Genetic
Background		 C57BL/6J-Cd247m1Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd247m1Btlr mutation (1 available); any Cd247 mutation (11 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal CD4-positive, alpha-beta T cell physiology ( J:158794 )
• following sublethal irradiation and repopulation with wild-type bone marrow cells, CD4+ T cells from homozygous mice are outcompeted by wild type cells

hematopoietic system
abnormal CD4-positive, alpha-beta T cell physiology ( J:158794 )
• following sublethal irradiation and repopulation with wild-type bone marrow cells, CD4+ T cells from homozygous mice are outcompeted by wild type cells




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory