About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(CD4-Il17re)#Cdon
transgene insertion, Chen Dong
MGI:5297501
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
 		Tg(CD4-Il17re)#Cdon/0 involves: C57BL/6 MGI:5297502


Genotype
MGI:5297502
tg1
Allelic
Composition		 Tg(CD4-Il17re)#Cdon/0
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(CD4-Il17re)#Cdon mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal interleukin secretion ( J:177650 )
• MOG35-55-stimulated splenocytes exhibit decreased IL17A, IL17F, and IL22 production compared with similarly treated wild-type cells
decreased interleukin-17 secretion ( J:177650 )
• MOG35-55-stimulated splenocytes exhibit decreased IL17A and IL17F production compared with similarly treated wild-type cells
increased susceptibility to experimental autoimmune encephalomyelitis ( J:177650 )
• with exacerbated symptoms and increased production of IL17A, IL17F, and IL22




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/22/2024
MGI 6.24 		The Jackson Laboratory