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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Fstl1tm1.1Mvdh
targeted mutation 1.1, Maurice JB van den Hoff
MGI:5297548
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Fstl1tm1.1Mvdh/Fstl1tm1.1Mvdh
Tg(Myh6-cre)2182Mds/0
involves: 129S4/SvJae * C57BL/6 * FVB/N MGI:5297552


Genotype
MGI:5297552
cn1
Allelic
Composition
Fstl1tm1.1Mvdh/Fstl1tm1.1Mvdh
Tg(Myh6-cre)2182Mds/0
Genetic
Background
involves: 129S4/SvJae * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fstl1tm1.1Mvdh mutation (0 available); any Fstl1 mutation (46 available)
Tg(Myh6-cre)2182Mds mutation (3 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• following pressure overload
• following pressure overload, the increase in myocardial capillary density is less than in wild-type mice
• following pressure overload
• following pressure overload, the increase in myocardial capillary density is less than in wild-type mice
• increased thickness following pressure overload
• following pressure overload
• following pressure overload
• increased left ventricular wall thickness following pressure overload
• following pressure overload
• following pressure overload
• increased left ventricular dimension and reduced fractional shortening following pressure overload
• following pressure overload, mice exhibit exacerbated cardiac myocyte hypertrophy and dysfunction compared with similarly treated wild-type mice

homeostasis/metabolism
• following pressure overload, mice exhibit exacerbated cardiac myocyte hypertrophy and dysfunction compared with similarly treated wild-type mice

muscle
• following pressure overload
• increased left ventricular dimension and reduced fractional shortening following pressure overload

respiratory system
• following pressure overload

growth/size/body
• following pressure overload
• following pressure overload





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory