mortality/aging
• mice do not survive beyond 8 weeks of age
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reproductive system
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• at 6 weeks of age
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• at 6 weeks of age
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endocrine/exocrine glands
• at E18.5 and 4 weeks of age
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• beginning at E13.5 and 4 weeks of age
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• at E13.5, E15.5, and E18.5
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homeostasis/metabolism
• in male mice at 3.5 week
• in male and female mice at 7 weeks of age
• at 6 weeks of age, female and male mice are severely diabetic under fed and fasted conditions unlike wild-type mice
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