mortality/aging
• at weaning, only 3.3% of pups are double homozygotes
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• slightly fewer embryos than expected are detected at E18.5
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respiratory system
• at E18.5 the lung mesenchyme is slightly thicker compared to controls
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growth/size/body
• surviving mice weigh less at 5, 10 and 15 weeks of age but catch up to controls by 20 weeks of age
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reproductive system
N |
• surviving adults are fertile
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