homeostasis/metabolism
• fibrogen binding is reduced compared to wild-type cells
• platelets exhibit defective agonist induced platelet integrin activation compared with wild-type mice
• however, binding in the presence of manganese is normal
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• clot retraction is impaired compared to in wild-type mice
• however, clot retraction in the presence of manganese is normal
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hematopoietic system
• fibrogen binding is reduced compared to wild-type cells
• platelets exhibit defective agonist induced platelet integrin activation compared with wild-type mice
• however, binding in the presence of manganese is normal
|