Phenotypes associated with this allele

• Allele Symbol: Emc4^{tm1(KOMP)Wtsi}
• Allele Name: targeted mutation 1, Wellcome Trust Sanger Institute
• Allele ID: MGI:5299564
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Emc4^tm1(KOMP)Wtsi/Emc4^tm1(KOMP)Wtsi	C57BL/6N-Emc4^tm1(KOMP)Wtsi/Nju	MGI:5767651
ht2	Emc4^tm1(KOMP)Wtsi/Emc4^+	C57BL/6N-Emc4^tm1(KOMP)Wtsi/Nju	MGI:5757044

Genotype
MGI:5767651

hm1

• Allelic Composition: Emc4^{tm1(KOMP)Wtsi}/Emc4^{tm1(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Emc4^{tm1(KOMP)Wtsi}/Nju
• Cell Lines: EPD0888_3_B01

Data Sources

IMPC Data for Emc4

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - MARC

Genotype
MGI:5757044

ht2

• Allelic Composition: Emc4^{tm1(KOMP)Wtsi}/Emc4⁺
• Genetic Background: C57BL/6N-Emc4^{tm1(KOMP)Wtsi}/Nju
• Cell Lines: EPD0888_3_B01

Data Sources

IMPC Data for Emc4

cardiovascular system

decreased heart left ventricle size ( J:211773 )

♀

IMPC - MARC

hematopoietic system

increased basophil cell number ( J:211773 )

♂

IMPC - MARC

increased eosinophil cell number ( J:211773 )

♂

IMPC - MARC

homeostasis/metabolism

increased fasting circulating glucose level ( J:211773 )

♀

IMPC - MARC

immune system

increased basophil cell number ( J:211773 )

♂

IMPC - MARC

increased eosinophil cell number ( J:211773 )

♂

IMPC - MARC

integument

abnormal coat/hair pigmentation ( J:211773 )

♀

IMPC - MARC

pigmentation

abnormal coat/hair pigmentation ( J:211773 )

♀

IMPC - MARC