Phenotypes associated with this allele

• Allele Symbol: Tg(MMTV-tTA)25755Kuw
• Allele Name: transgene insertion 25755, Kay-Uwe Wagner
• Allele ID: MGI:5300555
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Ccnd1^tm1Wbg/Ccnd1^tm1Wbg Tg(MMTV-tTA)25755Kuw/0 Tg(tetO-Ccnd1*T286A,-luc)10897Kuw/0	involves: 129S2/SvPas * FVB/N	MGI:5300579
cx2	Ccnd1^tm1Wbg/Ccnd1^tm1Wbg Tg(MMTV-tTA)25755Kuw/0 Tg(tetO-Ccnd1*T286A,-luc)11233Kuw/0	involves: 129S2/SvPas * FVB/N	MGI:5300584

Genotype
MGI:5300579

cx1

• Allelic Composition: Ccnd1^tm1Wbg/Ccnd1^tm1Wbg; Tg(MMTV-tTA)25755Kuw/0; Tg(tetO-Ccnd1*T286A,-luc)10897Kuw/0
• Genetic Background: involves: 129S2/SvPas * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

endocrine/exocrine gland phenotype ( J:178842 )

N • the mammary gland alveolar compartment develop normally

lactation failure ( J:178842 )

♀

integument

lactation failure ( J:178842 )

♀

Genotype
MGI:5300584

cx2

• Allelic Composition: Ccnd1^tm1Wbg/Ccnd1^tm1Wbg; Tg(MMTV-tTA)25755Kuw/0; Tg(tetO-Ccnd1*T286A,-luc)11233Kuw/0
• Genetic Background: involves: 129S2/SvPas * FVB/N

endocrine/exocrine glands

endocrine/exocrine gland phenotype ( J:178842 )

N • the mammary gland alveolar compartment develop normally

lactation failure ( J:178842 )

♀

integument

lactation failure ( J:178842 )

♀