Allele Symbol Allele Name Allele ID |
Mecp2tm1.1Meg targeted mutation 1.1, Michael E Greenberg MGI:5302542 |
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Summary |
2 genotypes
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
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• male mice are fertile
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• mice exhibit normal anxiety-related and motor behaviors, social approach, and spatial learning and memory
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• mice spend equal time investigating a novel objects or mouse as a familiar object or mouse unlike wild-type mice
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• mice spend equal time investigating a novel objects as a familiar object unlike wild-type mice
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• cultured cortical neurons exhibit an increase in the average number of dendritic branches and increased dendritic complexity compared with wild-type cells
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• increased amplitude
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/27/2024 MGI 6.24 |
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