Phenotypes associated with this allele

• Allele Symbol: Trpv5^m1Btlr
• Allele Name: mutation 1, Bruce Beutler
• Allele ID: MGI:5304494
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Trpv5^m1Btlr/Trpv5^m1Btlr	C57BL/6J-Trpv5^m1Btlr	MGI:5465451

Genotype
MGI:5465451

hm1

• Allelic Composition: Trpv5^m1Btlr/Trpv5^m1Btlr
• Genetic Background: C57BL/6J-Trpv5^m1Btlr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

renal/urinary system

polyuria ( J:192586 )

behavior/neurological

polydipsia ( J:192586 )

• probably due to polyuria

digestive/alimentary system

diarrhea ( J:192586 )

intestinal inflammation ( J:192586 )

• bleeding

• possibly due to increased dextran sodium sulfate increase because of increased water intake

increased susceptibility to induced colitis ( J:192586 )

• susceptible to dextran sulfate sodium (DSS)-induced colitis

• susceptible to low doses of DSS (1%)

immune system

intestinal inflammation ( J:192586 )

• bleeding

• possibly due to increased dextran sodium sulfate increase because of increased water intake

increased susceptibility to induced colitis ( J:192586 )

• susceptible to dextran sulfate sodium (DSS)-induced colitis

• susceptible to low doses of DSS (1%)

growth/size/body

weight loss ( J:192586 )

• severe weight loss