All Phenotypes Notch1<tm1.1(cre/ERT2)Sat> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Notch1^{tm1.1(cre/ERT2)Sat}
targeted mutation 1.1, Spyros Artavanis-Tsakonas
MGI:5304912

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Notch1^{tm1.1(cre/ERT2)Sat}/Notch1^{tm1.1(cre/ERT2)Sat}	C57BL/6-Notch1^{tm1.1(cre/ERT2)Sat}	MGI:5304922
ht2	Notch1^{tm1.1(cre/ERT2)Sat}/Notch1⁺	C57BL/6-Notch1^{tm1.1(cre/ERT2)Sat}	MGI:5304923

Allelic Composition	Notch1^{tm1.1(cre/ERT2)Sat}/Notch1^{tm1.1(cre/ERT2)Sat}
Genetic Background	C57BL/6-Notch1^{tm1.1(cre/ERT2)Sat}

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Notch1^{tm1.1(cre/ERT2)Sat} mutation (0 available); any Notch1 mutation (117 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality ( J:179632 )

• homozygotes die during embryogenesis, like Notch1^tm1Grid embryos

Allelic Composition	Notch1^{tm1.1(cre/ERT2)Sat}/Notch1⁺
Genetic Background	C57BL/6-Notch1^{tm1.1(cre/ERT2)Sat}

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Notch1^{tm1.1(cre/ERT2)Sat} mutation (0 available); any Notch1 mutation (117 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

normal phenotype

no abnormal phenotype detected ( J:179632 )

• heterozygotes are viable and fertile

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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