All Phenotypes Notch2<tm1.1(cre/ERT2)Sat> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Notch2^{tm1.1(cre/ERT2)Sat}
targeted mutation 1.1, Spyros Artavanis-Tsakonas
MGI:5304913

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Notch2^{tm1.1(cre/ERT2)Sat}/Notch2^{tm1.1(cre/ERT2)Sat}	C57BL/6-Notch2^{tm1.1(cre/ERT2)Sat}	MGI:5304924
ht2	Notch2^{tm1.1(cre/ERT2)Sat}/Notch2⁺	C57BL/6-Notch2^{tm1.1(cre/ERT2)Sat}	MGI:5304925

Allelic Composition	Notch2^{tm1.1(cre/ERT2)Sat}/Notch2^{tm1.1(cre/ERT2)Sat}
Genetic Background	C57BL/6-Notch2^{tm1.1(cre/ERT2)Sat}

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Notch2^{tm1.1(cre/ERT2)Sat} mutation (0 available); any Notch2 mutation (99 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality ( J:179632 )

• homozygotes die during embryogenesis, like Notch2^tm1Yha embryos

Allelic Composition	Notch2^{tm1.1(cre/ERT2)Sat}/Notch2⁺
Genetic Background	C57BL/6-Notch2^{tm1.1(cre/ERT2)Sat}

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Notch2^{tm1.1(cre/ERT2)Sat} mutation (0 available); any Notch2 mutation (99 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

normal phenotype

no abnormal phenotype detected ( J:179632 )

• heterozygotes are viable and fertile

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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