All Phenotypes Jup<tm1.1Tmj> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Jup^tm1.1Tmj
targeted mutation 1.1, Thomas M Jessell
MGI:5305426

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Ctnnb1^tm2Kem/Ctnnb1^tm2Kem Jup^tm1Ruiz/Jup^tm1.1Tmj Olig2^tm1(cre)Tmj/Olig2⁺	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ	MGI:5305439

Allelic Composition	Ctnnb1^tm2Kem/Ctnnb1^tm2Kem Jup^tm1Ruiz/Jup^tm1.1Tmj Olig2^tm1(cre)Tmj/Olig2⁺
Genetic Background	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ctnnb1^tm2Kem mutation (1 available); any Ctnnb1 mutation (49 available)
Jup^tm1.1Tmj mutation (1 available); any Jup mutation (162 available)
Jup^tm1Ruiz mutation (1 available); any Jup mutation (162 available)
Olig2^tm1(cre)Tmj mutation (0 available); any Olig2 mutation (46 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

lethality throughout fetal growth and development, complete penetrance ( J:178688 )

• mice only survive until E14.5

nervous system

abnormal dendrite morphology ( J:178688 )

• at E14.5, motor neuron dendrite length and primary branch number are reduced 2- to 3-fold compared with control dendrites

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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