All Phenotypes Gt(ROSA)26Sor<tm1(CAG-Bmpr1a)Que> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Gt(ROSA)26Sor^{tm1(CAG-Bmpr1a)Que}
targeted mutation 1, Jianwen Que
MGI:5305709

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Gt(ROSA)26Sor^{tm1(CAG-Bmpr1a)Que}/Gt(ROSA)26Sor⁺ Shh^{tm1(EGFP/cre)Cjt}/?	Not Specified	MGI:5305711

Allelic Composition	Gt(ROSA)26Sor^{tm1(CAG-Bmpr1a)Que}/Gt(ROSA)26Sor⁺ Shh^{tm1(EGFP/cre)Cjt}/?
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sor^{tm1(CAG-Bmpr1a)Que} mutation (0 available); any Gt(ROSA)26Sor mutation (993 available)
Shh^{tm1(EGFP/cre)Cjt} mutation (1 available); any Shh mutation (48 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:166768 )

• all heterozygotes die before 5 days of age

digestive/alimentary system

abnormal esophageal epithelium morphology ( J:166768 )

• simple columnar epithelial cells along the esophagus at E15.5, primarily ventrally

abnormal forestomach morphology ( J:166768 )

• scattered appearance of simple columnar epithelium in the forestomach at E15.5 and at birth

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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