Allele Symbol Allele Name Allele ID |
Apctm1.1Alew targeted mutation 1.1, Anabelle Lewis MGI:5305725 |
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Summary |
2 genotypes
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• mice exhibit increased incidents and polyp size with more frequent paneth cell differentiation and polyp crypt fission with normal tissue compared with ApcMin heterozygotes
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• gastric and intestinal
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• however, no carcinomas are observed
(J:180057)
• adenoma gastrointestinal polyps, greatest in the small intestine
(J:180275)
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• however, no carcinomas are observed
(J:180057)
• adenoma gastrointestinal polyps, greatest in the small intestine
(J:180275)
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• adenoma gastrointestinal polyps, greatest in the small intestine
(J:180275)
• severe polyposis with increased incidents and polyp size compared with ApcMin heterozygotes
(J:180275)
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• in polyps
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• in polyps
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• mice are euthanized by 12 weeks of age due to symptoms of anemia
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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