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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
m1078Lja
mutation 1078, J Larry Jameson
MGI:5306137
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
m1078Lja/m1078Lja involves: C57BL/6J * DBA MGI:5306141


Genotype
MGI:5306141
hm1
Allelic
Composition
m1078Lja/m1078Lja
Genetic
Background
involves: C57BL/6J * DBA
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
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phenotype observed in females
phenotype observed in males
N normal phenotype

Hypogonadism with germ cell deficiency in m1078Lja/m1078Lja males

reproductive system
• every tubule exhibits substantial germ cell deficiency
• the most affected tubules containing only Sertoli cells while other tubules contain only premeiotic cells many tubules contain cells with condensed, pyknotic nuclei
• severe hypogonadism in males

endocrine/exocrine glands
• severe hypogonadism in males

cellular
• every tubule exhibits substantial germ cell deficiency
• the most affected tubules containing only Sertoli cells while other tubules contain only premeiotic cells many tubules contain cells with condensed, pyknotic nuclei





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory