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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Nr3c1tm1.1Mvc
targeted mutation 1.1, Moses V Chao
MGI:5306342
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Nr3c1tm1.1Mvc/Nr3c1tm1.1Mvc
Tg(Sim1-cre)1Lowl/0 		involves: 129 * C57BL/6 * FVB MGI:5306343
cn2
 		Nr3c1tm1.1Mvc/Nr3c1+
Tg(Sim1-cre)1Lowl/0 		involves: 129 * C57BL/6 * FVB MGI:5306344


Genotype
MGI:5306343
cn1
Allelic
Composition		 Nr3c1tm1.1Mvc/Nr3c1tm1.1Mvc
Tg(Sim1-cre)1Lowl/0
Genetic
Background		 involves: 129 * C57BL/6 * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nr3c1tm1.1Mvc mutation (0 available); any Nr3c1 mutation (35 available)
Tg(Sim1-cre)1Lowl mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging




Genotype
MGI:5306344
cn2
Allelic
Composition		 Nr3c1tm1.1Mvc/Nr3c1+
Tg(Sim1-cre)1Lowl/0
Genetic
Background		 involves: 129 * C57BL/6 * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nr3c1tm1.1Mvc mutation (0 available); any Nr3c1 mutation (35 available)
Tg(Sim1-cre)1Lowl mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
decreased body weight ( J:179918 )
• during adulthood

homeostasis/metabolism

nervous system
abnormal hypothalamus physiology ( J:179918 )
• elevated immunoreactivity for corticotropin-releasing hormone in the paraventricular nucleus




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory