Analysis Tools
immune system
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• following injection of the neuropeptide calcitonin gene-related peptide (CGRP), mutants exhibit a greater dye leakage in the whiskerpads than control mice, indicating enhanced subcutaneous facial plasma extravasation, a measure of neurogenic inflammation, in response to CGRP receptor activity
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behavior/neurological
photophobia
(
J:179493
)
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• mutants exhibit a light-aversive behavior (photophobic phenotype), spending less time in the light than controls
• light-aversive behavior is seen in untreated mutants and is enhanced by CGRP treatment
• mutants exhibit decreased mobility in response to CGRP in the dark, but not the light side of the chamber
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homeostasis/metabolism
photophobia
(
J:179493
)
|
• mutants exhibit a light-aversive behavior (photophobic phenotype), spending less time in the light than controls
• light-aversive behavior is seen in untreated mutants and is enhanced by CGRP treatment
• mutants exhibit decreased mobility in response to CGRP in the dark, but not the light side of the chamber
|
vision/eye
photophobia
(
J:179493
)
|
• mutants exhibit a light-aversive behavior (photophobic phenotype), spending less time in the light than controls
• light-aversive behavior is seen in untreated mutants and is enhanced by CGRP treatment
• mutants exhibit decreased mobility in response to CGRP in the dark, but not the light side of the chamber
|
