About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cd40lgtm1Parl
targeted mutation 1, Roberto Parrilla
MGI:5306631
Summary 6 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Cd40lgtm1Parl/Cd40lgtm1Parl
Commd10Tg(Vav1-icre)A2Kio/Commd10+ 		involves: 129 * C57BL/6 * C57BL/10 * CBA/Ca MGI:5585442
cn2
 		Cd40lgtm1Parl/Y
Commd10Tg(Vav1-icre)A2Kio/Commd10+ 		involves: 129 * C57BL/6 * C57BL/10 * CBA/Ca MGI:5585443
cn3
 		Cd40lgtm1Parl/Y
Tg(Tek-cre)1Ywa/0 		involves: 129 * C57BL/6 * CD-1 * SJL MGI:5585444
cn4
 		Cd40lgtm1Parl/Cd40lgtm1Parl
Tg(Tek-cre)1Ywa/0 		involves: 129 * C57BL/6 * CD-1 * SJL MGI:5585446
cn5
 		Cd40lgtm1Parl/Y
Tg(Cd4-cre)1Cwi/0 		involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2 MGI:5585440
cn6
 		Cd40lgtm1Parl/Cd40lgtm1Parl
Tg(Cd4-cre)1Cwi/0 		involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2 MGI:5585441


Genotype
MGI:5585442
cn1
Allelic
Composition		 Cd40lgtm1Parl/Cd40lgtm1Parl
Commd10Tg(Vav1-icre)A2Kio/Commd10+
Genetic
Background		 involves: 129 * C57BL/6 * C57BL/10 * CBA/Ca
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd40lgtm1Parl mutation (0 available); any Cd40lg mutation (17 available)
Commd10Tg(Vav1-icre)A2Kio mutation (3 available); any Commd10 mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
hematopoietic system phenotype ( J:213459 )
N
• mice exhibit normal hemograms
thrombocytopenia ( J:213459 )
• decreased circulating platelets 2 min after administration of agonists

homeostasis/metabolism
homeostasis/metabolism phenotype ( J:213459 )
N
• mice exhibit normal prothrombin tine and activated partial thromboplastin time

immune system




Genotype
MGI:5585443
cn2
Allelic
Composition		 Cd40lgtm1Parl/Y
Commd10Tg(Vav1-icre)A2Kio/Commd10+
Genetic
Background		 involves: 129 * C57BL/6 * C57BL/10 * CBA/Ca
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd40lgtm1Parl mutation (0 available); any Cd40lg mutation (17 available)
Commd10Tg(Vav1-icre)A2Kio mutation (3 available); any Commd10 mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
hematopoietic system phenotype ( J:213459 )
N
• mice exhibit normal hemograms
thrombocytopenia ( J:213459 )
• decreased circulating platelets 2 min after administration of agonists

homeostasis/metabolism
homeostasis/metabolism phenotype ( J:213459 )
N
• mice exhibit normal prothrombin tine and activated partial thromboplastin time

immune system




Genotype
MGI:5585444
cn3
Allelic
Composition		 Cd40lgtm1Parl/Y
Tg(Tek-cre)1Ywa/0
Genetic
Background		 involves: 129 * C57BL/6 * CD-1 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd40lgtm1Parl mutation (0 available); any Cd40lg mutation (17 available)
Tg(Tek-cre)1Ywa mutation (6 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
hematopoietic system phenotype ( J:213459 )
N
• mice exhibit normal hemograms and response to thromogenesis

homeostasis/metabolism
homeostasis/metabolism phenotype ( J:213459 )
N
• mice exhibit normal prothrombin tine and activated partial thromboplastin time

immune system




Genotype
MGI:5585446
cn4
Allelic
Composition		 Cd40lgtm1Parl/Cd40lgtm1Parl
Tg(Tek-cre)1Ywa/0
Genetic
Background		 involves: 129 * C57BL/6 * CD-1 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd40lgtm1Parl mutation (0 available); any Cd40lg mutation (17 available)
Tg(Tek-cre)1Ywa mutation (6 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
hematopoietic system phenotype ( J:213459 )
N
• mice exhibit normal hemograms and response to thromogenesis

homeostasis/metabolism
homeostasis/metabolism phenotype ( J:213459 )
N
• mice exhibit normal prothrombin tine and activated partial thromboplastin time

immune system




Genotype
MGI:5585440
cn5
Allelic
Composition		 Cd40lgtm1Parl/Y
Tg(Cd4-cre)1Cwi/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd40lgtm1Parl mutation (0 available); any Cd40lg mutation (17 available)
Tg(Cd4-cre)1Cwi mutation (10 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
hematopoietic system phenotype ( J:213459 )
N
• mice exhibit normal hemograms and response to thromogenesis

homeostasis/metabolism
homeostasis/metabolism phenotype ( J:213459 )
N
• mice exhibit normal prothrombin tine and activated partial thromboplastin time

immune system
immune system phenotype ( J:213459 )
N
• Igs levels are normal




Genotype
MGI:5585441
cn6
Allelic
Composition		 Cd40lgtm1Parl/Cd40lgtm1Parl
Tg(Cd4-cre)1Cwi/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd40lgtm1Parl mutation (0 available); any Cd40lg mutation (17 available)
Tg(Cd4-cre)1Cwi mutation (10 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
hematopoietic system phenotype ( J:213459 )
N
• mice exhibit normal hemograms and response to thromogenesis

homeostasis/metabolism
homeostasis/metabolism phenotype ( J:213459 )
N
• mice exhibit normal prothrombin tine and activated partial thromboplastin time

immune system
immune system phenotype ( J:213459 )
N
• Igs levels are normal




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory