About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Mirc21tm1.1Lhe
targeted mutation 1.1, Lin He
MGI:5308794
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Mirc21tm1.1Lhe/Mirc21tm1.1Lhe involves: 129S4/SvJae * C57BL/6 MGI:5308798
cx2
Mir34atm1.1Lhe/Mir34atm1.1Lhe
Mirc21tm1.1Lhe/Mirc21tm1.1Lhe
involves: 129S4/SvJae * C57BL/6 * C57BL/6J MGI:5308800


Genotype
MGI:5308798
hm1
Allelic
Composition
Mirc21tm1.1Lhe/Mirc21tm1.1Lhe
Genetic
Background
involves: 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mirc21tm1.1Lhe mutation (1 available); any Mirc21 mutation (5 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
• un-induced mouse embryonic fibroblasts exhibit an increase in reprogramming efficiency and generation of induced pluripotent stem cell compared with wild-type cells




Genotype
MGI:5308800
cx2
Allelic
Composition
Mir34atm1.1Lhe/Mir34atm1.1Lhe
Mirc21tm1.1Lhe/Mirc21tm1.1Lhe
Genetic
Background
involves: 129S4/SvJae * C57BL/6 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mir34atm1.1Lhe mutation (1 available); any Mir34a mutation (9 available)
Mirc21tm1.1Lhe mutation (1 available); any Mirc21 mutation (5 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
N
• induced pluripotent stem cells (iPSCs) resemble wild-type iPSCs
• un-induced mouse embryonic fibroblasts exhibit an increase in reprogramming efficiency and generation of iPSCs compared with wild-type and single homozygous cells





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/05/2024
MGI 6.24
The Jackson Laboratory