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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Mirc21tm1.1Lhe
targeted mutation 1.1, Lin He
MGI:5308794
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Mirc21tm1.1Lhe/Mirc21tm1.1Lhe involves: 129S4/SvJae * C57BL/6 MGI:5308798
cx2
Mir34atm1.1Lhe/Mir34atm1.1Lhe
Mirc21tm1.1Lhe/Mirc21tm1.1Lhe
involves: 129S4/SvJae * C57BL/6 * C57BL/6J MGI:5308800


Genotype
MGI:5308798
hm1
Allelic
Composition
Mirc21tm1.1Lhe/Mirc21tm1.1Lhe
Genetic
Background
involves: 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mirc21tm1.1Lhe mutation (1 available); any Mirc21 mutation (5 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
• un-induced mouse embryonic fibroblasts exhibit an increase in reprogramming efficiency and generation of induced pluripotent stem cell compared with wild-type cells




Genotype
MGI:5308800
cx2
Allelic
Composition
Mir34atm1.1Lhe/Mir34atm1.1Lhe
Mirc21tm1.1Lhe/Mirc21tm1.1Lhe
Genetic
Background
involves: 129S4/SvJae * C57BL/6 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mir34atm1.1Lhe mutation (1 available); any Mir34a mutation (9 available)
Mirc21tm1.1Lhe mutation (1 available); any Mirc21 mutation (5 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
N
• induced pluripotent stem cells (iPSCs) resemble wild-type iPSCs
• un-induced mouse embryonic fibroblasts exhibit an increase in reprogramming efficiency and generation of iPSCs compared with wild-type and single homozygous cells





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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory