Phenotypes associated with this allele

• Allele Symbol: Smurf2^tm1Yez
• Allele Name: targeted mutation 1, Ying E Zhang
• Allele ID: MGI:5308952
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Smurf2^tm1Yez/Smurf2^tm1Yez	either: B6.129S6-Smurf2^tm1Yez or (involves: 129S6/SvEvTac * NIH Black Swiss)	MGI:5308965

Genotype
MGI:5308965

hm1

• Allelic Composition: Smurf2^tm1Yez/Smurf2^tm1Yez
• Genetic Background: either: B6.129S6-Smurf2^tm1Yez or (involves: 129S6/SvEvTac * NIH Black Swiss)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

limbs/digits/tail

abnormal tail morphology ( J:180221 )

• occasionally kinky or looped tail

kinked tail ( J:180221 )

• occasionally

nervous system

hydrocephaly ( J:180221 )

• occasionally

cellular

abnormal cell physiology ( J:180221 )

• mouse embryonic fibroblasts exhibit enhanced responses to TGF-beta

skeleton

abnormal vertebrae morphology ( J:180221 )