Phenotypes associated with this allele

• Allele Symbol: Tg(CD2-NPM/ALK)4Sudt
• Allele Name: transgene insertion 4, Suzanne Turner
• Allele ID: MGI:5310806
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(CD2-NPM/ALK)4Sudt/0	involves: C57BL/6J * CBA	MGI:5310807

Genotype
MGI:5310807

tg1

• Allelic Composition: Tg(CD2-NPM/ALK)4Sudt/0
• Genetic Background: involves: C57BL/6J * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

increased liver tumor incidence ( J:181238 )

• the most common non-hemolyphoid site of tumor occurence in these transgenic mice is the liver

increased hemolymphoid system tumor incidence ( J:181238 )

• tumors, primarily B-cell lymphomas, of the thymus, spleen and various lymph nodes are common in mice bearing this transgene

increased B cell derived lymphoma incidence ( J:181238 )

• >= 40% of mice with this transgene develop tumors of hematopoietic origin, the great majority B-cell lymphomas, with long (9 mo +) latency in organs of the hemolymphoid system (thymus, spleen and various lymph nodes) and the liver, and occasionally in other organs or tissues

liver/biliary system

increased liver tumor incidence ( J:181238 )

• the most common non-hemolyphoid site of tumor occurence in these transgenic mice is the liver