Phenotypes associated with this allele

• Allele Symbol: b2b1249Clo
• Allele Name: Bench to Bassinet Program (B2B/CVDC), mutation 1249 Cecilia Lo
• Allele ID: MGI:5311391
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	b2b1249Clo/b2b1249Clo	C57BL/6J-b2b1249Clo	MGI:5442121

Genotype
MGI:5442121

hm1

• Allelic Composition: b2b1249Clo/b2b1249Clo
• Genetic Background: C57BL/6J-b2b1249Clo

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Persistent truncus arteriosus (PTA) and right aortic arch (RAA) in mutant 1249-007-1 (E16.5)

cardiovascular system

pulmonary artery hypoplasia ( J:175213 )

interrupted aortic arch, type b ( J:175213 )

right aortic arch ( J:175213 )

vascular ring ( J:175213 )

abnormal right subclavian artery morphology ( J:175213 )

double outlet right ventricle ( J:175213 )

right atrial isomerism ( J:175213 )

abnormal heart right atrium morphology ( J:175213 )

craniofacial

cleft palate ( J:175213 )

digestive/alimentary system

cleft palate ( J:175213 )

growth/size/body

cleft palate ( J:175213 )

heterotaxia ( J:175213 )

right atrial isomerism ( J:175213 )

hematopoietic system

thymus hypoplasia ( J:175213 )

immune system

thymus hypoplasia ( J:175213 )

limbs/digits/tail

polydactyly ( J:175213 )

renal/urinary system

renal hypoplasia ( J:175213 )

respiratory system

pulmonary hypoplasia ( J:175213 )

skeleton

decreased rib number ( J:175213 )

• missing pair of caudal sternal ribs

endocrine/exocrine glands

thymus hypoplasia ( J:175213 )