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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Casp8ap2Gt(SGT207T1)Tigm
gene trap SGT207T1, Texas A&M Institute for Genomic Medicine
MGI:5311557
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Casp8ap2Gt(SGT207T1)Tigm/Casp8ap2Gt(SGT207T1)Tigm involves: 129S/SvEvBrd * C57BL/6J MGI:5311562


Genotype
MGI:5311562
hm1
Allelic
Composition		 Casp8ap2Gt(SGT207T1)Tigm/Casp8ap2Gt(SGT207T1)Tigm
Genetic
Background		 involves: 129S/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Casp8ap2Gt(SGT207T1)Tigm mutation (0 available); any Casp8ap2 mutation (77 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality before implantation, complete penetrance ( J:181069 )
• homozygous zygotes die in culture by E4.5
• developmental retardation and some death by E3.5
• none reach the blastocyst stage in culture
• no homozygous embryos found at E8.5




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory