All Phenotypes Fzd4<tm1.1Lex> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Fzd4^tm1.1Lex
targeted mutation 1.1, Lexicon Genetics
MGI:5312687

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fzd4^tm1.1Lex/Fzd4^tm1.1Lex	involves: 129S5/SvEvBrd * C57BL/6	MGI:5312691

Allelic Composition	Fzd4^tm1.1Lex/Fzd4^tm1.1Lex
Genetic Background	involves: 129S5/SvEvBrd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fzd4^tm1.1Lex mutation (0 available); any Fzd4 mutation (31 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

cardiovascular system phenotype ( J:181399 )

N	• mice exhibit normal choriocapillaris

decreased angiogenesis ( J:181399 )

• the superficial vascular plexus exhibits decreased complexity and vascular progression towards the retinal periphery compared to in wild-type mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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