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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Hprt1tm2(CAG-TBX2,-EGFP)Akis
targeted mutation 2, Andreas Kispert
MGI:5314539
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Hprt1tm2(CAG-TBX2,-EGFP)Akis/Hprt1+
Tg(Myh6-cre)2182Mds/0 		involves: 129 * FVB/N * NMRI MGI:5314543


Genotype
MGI:5314543
cn1
Allelic
Composition		 Hprt1tm2(CAG-TBX2,-EGFP)Akis/Hprt1+
Tg(Myh6-cre)2182Mds/0
Genetic
Background		 involves: 129 * FVB/N * NMRI
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hprt1tm2(CAG-TBX2,-EGFP)Akis mutation (0 available); any Hprt1 mutation (1279 available)
Tg(Myh6-cre)2182Mds mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal heart development ( J:181526 )
• mice exhibit ectopic sub-endocardial mesenchyme in the atria and to a lesser extent in the ventricles unlike in control mice
• mice exhibit abnormal cardiac jelly and cushion formation in chamber myocardium compared with control mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory