All Phenotypes Elavl1<tm1.1Bndr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Elavl1^tm1.1Bndr
targeted mutation 1.1, Jeffrey R Bender
MGI:5316082

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Elavl1^tm1.1Bndr/Elavl1^tm1.1Bndr Lyz2^tm1(cre)Ifo/Lyz2⁺	B6.129-Elavl1^tm1.1Bndr	MGI:5316084

Allelic Composition	Elavl1^tm1.1Bndr/Elavl1^tm1.1Bndr Lyz2^tm1(cre)Ifo/Lyz2⁺
Genetic Background	B6.129-Elavl1^tm1.1Bndr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Elavl1^tm1.1Bndr mutation (0 available); any Elavl1 mutation (43 available)
Lyz2^tm1(cre)Ifo mutation (14 available); any Lyz2 mutation (40 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

abnormal capillary morphology ( J:182000 )

• fewer capillaries per muscle fiber in gastrocnemius after induced hind limb ischemia

abnormal physiological neovascularization ( J:182000 )

• reduced microvessel formation in sterile sponges implanted subdermally

• reduced VEGF and MMP-9 in sterile sponges implanted subdermally

abnormal blood circulation ( J:182000 )

• considerable attenuation of blood flow in the gastrocnemius after induced hind limb ischemia

cellular

cellular necrosis ( J:182000 )

• higher level of necrosis in the paws of the hind limb at 2 weeks after induced hind limb ischemia

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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