All Phenotypes Topbp1<tm1Pmc> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Topbp1^tm1Pmc
targeted mutation 1, Peter J McKinnon
MGI:5316209

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Emx1^tm1(cre)Krj/Emx1⁺ Topbp1^tm1Pmc/Topbp1^tm1Pmc	involves: 129S2/SvPas * C57BL/6J	MGI:5316226

Allelic Composition	Emx1^tm1(cre)Krj/Emx1⁺ Topbp1^tm1Pmc/Topbp1^tm1Pmc
Genetic Background	involves: 129S2/SvPas * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Emx1^tm1(cre)Krj mutation (2 available); any Emx1 mutation (34 available)
Topbp1^tm1Pmc mutation (0 available); any Topbp1 mutation (76 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal cerebral cortex morphology ( J:181920 )

• extensive cortical ablation

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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