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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Slc26a5tm4.1(cre/ERT2)Jnz
targeted mutation 4.1, Jian Zou
MGI:5316512
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Slc26a5tm4.1(cre/ERT2)Jnz/Slc26a5tm4.1(cre/ERT2)Jnz involves: 129S6/SvEvTac * C57BL/6 MGI:5316666
ht2
 		Slc26a5tm4.1(cre/ERT2)Jnz/Slc26a5+ involves: 129S6/SvEvTac * C57BL/6 MGI:5316600


Genotype
MGI:5316666
hm1
Allelic
Composition		 Slc26a5tm4.1(cre/ERT2)Jnz/Slc26a5tm4.1(cre/ERT2)Jnz
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc26a5tm4.1(cre/ERT2)Jnz mutation (0 available); any Slc26a5 mutation (58 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hearing/vestibular/ear
increased or absent threshold for auditory brainstem response ( J:182720 )
• some (7/11) mice have increased have elevated ABR thresholds at 16 and 22 kHz compared to controls; this is attributed to substantial C57BL/6 contribution to the background of the mice (postulated by authors)




Genotype
MGI:5316600
ht2
Allelic
Composition		 Slc26a5tm4.1(cre/ERT2)Jnz/Slc26a5+
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc26a5tm4.1(cre/ERT2)Jnz mutation (0 available); any Slc26a5 mutation (58 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hearing/vestibular/ear
hearing/vestibular/ear phenotype ( J:182720 )
N
• mice display normal ABR thresholds at all frequencies tested




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory