All Phenotypes Smad6<b2b390Clo> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Smad6^b2b390Clo
Bench to Bassinet Program (B2B/CvDC), mutation 390 Cecilia Lo
MGI:5316777

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Smad6^b2b390Clo/Smad6^b2b390Clo	C57BL/6J-Smad6^b2b390Clo	MGI:5316791

Allelic Composition	Smad6^b2b390Clo/Smad6^b2b390Clo
Genetic Background	C57BL/6J-Smad6^b2b390Clo

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Smad6^b2b390Clo mutation (1 available); any Smad6 mutation (24 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

2D serial EFIC image stack in the coronal view of mutant 390-006-1 (E14.5) reveals DORV {SDD}, subaortic VSD, and interrupted aortic arch (IAA type c)
Click thumbnail to play movie.

cardiovascular system

double outlet right ventricle ( J:175213 )

overriding aortic valve ( J:175213 )

d-loop transposition of the great arteries ( J:175213 )

tricuspid valve atresia ( J:175213 )

perimembraneous ventricular septal defect ( J:175213 )

muscular ventricular septal defect ( J:175213 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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