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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Eya1tm2Px
targeted mutation 2, Pin-Xian Xu
MGI:5316865
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Eya1tm2Px/Eya1tm2Px
Tg(Atoh1-cre/Esr1*)14Fsh/0
involves: 129S1/Sv * 129X1/SvJ * FVB/N MGI:5316867


Genotype
MGI:5316867
cn1
Allelic
Composition
Eya1tm2Px/Eya1tm2Px
Tg(Atoh1-cre/Esr1*)14Fsh/0
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Eya1tm2Px mutation (0 available); any Eya1 mutation (56 available)
Tg(Atoh1-cre/Esr1*)14Fsh mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
hearing/vestibular/ear
• hair cells in the basal and medial turns of the cochlea from tamoxifen-treated mice exhibit abnormalities that disappear when cultured in vitro
• tamoxifen-treated mice lack hair cells in the apical turn of the cochlea with outer rows more affected than inner rows
• tamoxifen-treated mice lack hair cells in the apical turn of the cochlea with outer rows more affected than inner rows

nervous system
• hair cells in the basal and medial turns of the cochlea from tamoxifen-treated mice exhibit abnormalities that disappear when cultured in vitro
• tamoxifen-treated mice lack hair cells in the apical turn of the cochlea with outer rows more affected than inner rows
• tamoxifen-treated mice lack hair cells in the apical turn of the cochlea with outer rows more affected than inner rows





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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory