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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Piwil1tm1.1Embrp
targeted mutation 1.1, Ramesh Pillai
MGI:5316870
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
Piwil1tm1.1Embrp/Piwil1+ involves: 129S4/SvJaeSor * C57BL/6 MGI:5316873
ht2
Piwil1tm1.1Embrp/Piwil1tm1.2Embrp involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6 MGI:5316875


Genotype
MGI:5316873
ht1
Allelic
Composition
Piwil1tm1.1Embrp/Piwil1+
Genetic
Background
involves: 129S4/SvJaeSor * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Piwil1tm1.1Embrp mutation (1 available); any Piwil1 mutation (28 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
N
• female mice exhibit normal fertility
• mutant sperm degenerate in the epididymis
• with abnormal nuclear morphologies

cellular
• mutant sperm degenerate in the epididymis
• with abnormal nuclear morphologies




Genotype
MGI:5316875
ht2
Allelic
Composition
Piwil1tm1.1Embrp/Piwil1tm1.2Embrp
Genetic
Background
involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Piwil1tm1.1Embrp mutation (1 available); any Piwil1 mutation (28 available)
Piwil1tm1.2Embrp mutation (1 available); any Piwil1 mutation (28 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• accumulation of ribonucleaoprotein granules (chromatoid bodies)
• after meiosis at haploid round spermatids

cellular
• accumulation of ribonucleaoprotein granules (chromatoid bodies)





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory