Analysis Tools
nervous system
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• spontaneous beginning in the second postnatal week (P10), especially during cage changing and handling
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• during cage changing and handling
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• increased thickness
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• mossy fibers in temporal lobe epilepsies often sprout aberrant recurrent synapses with dentate granule cells
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• abnormal dispersion at P14 after the onset of seizures
• mossy fibers in temporal lobe epilepsies often sprout aberrant recurrent synapses with dentate granule cells
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• at P14 after the onset of seizures, particularly in the hilus of the dentate gyrus
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• following the onset of seizures
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• mice exhibit ictal epileptic electroencephalogram abnormalities, often bilateral, compared with wild-type mice
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growth/size/body
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• at P14
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• at P14
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• between P10 and P14
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behavior/neurological
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• mice lack stomach contents at death and likely die of dehydration and/or starvation
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• spontaneous beginning in the second postnatal week (P10), especially during cage changing and handling
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• during cage changing and handling
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adipose tissue
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• lack of body fact at P14
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mortality/aging
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• mean lifetime of 16 days; no mice survive beyond P21
• mice lack stomach contents at death and likely die of dehydration and/or starvation
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Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
| familial temporal lobe epilepsy 1 | DOID:0060748 |
OMIM:600512 |
J:182795 | |
