All Phenotypes Gjc1<tm1.2(Gjd2)Kwi> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Gjc1^{tm1.2(Gjd2)Kwi}
targeted mutation 1.2, Klaus Willecke
MGI:5317163

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gjc1^{tm1.2(Gjd2)Kwi}/Gjc1^{tm1.2(Gjd2)Kwi}	involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SJL	MGI:5317175

Allelic Composition	Gjc1^{tm1.2(Gjd2)Kwi}/Gjc1^{tm1.2(Gjd2)Kwi}
Genetic Background	involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gjc1^{tm1.2(Gjd2)Kwi} mutation (0 available); any Gjc1 mutation (33 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:182927 )

• at E11.5

cardiovascular system

enlarged heart ( J:182927 )

decreased cardiac muscle contractility ( J:182927 )

• the heart contracts weakly until E11.5

embryo

embryonic growth retardation ( J:182927 )

• at E10.5 and E11.5

decreased embryo size ( J:182927 )

• at E10.5 and E11.5

growth/size/body

enlarged heart ( J:182927 )

embryonic growth retardation ( J:182927 )

• at E10.5 and E11.5

decreased embryo size ( J:182927 )

• at E10.5 and E11.5

muscle

decreased cardiac muscle contractility ( J:182927 )

• the heart contracts weakly until E11.5

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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