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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Slc29a1tm2Msg
targeted mutation 2, Robert O Messing
MGI:5317195
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Slc29a1tm2Msg/Slc29a1tm2Msg
Eportm1.1(EGFP/icre)Uk/Epor+ 		involves: 129X1/SvJ * BALB/cJ MGI:6151074


Genotype
MGI:6151074
cn1
Allelic
Composition		 Slc29a1tm2Msg/Slc29a1tm2Msg
Eportm1.1(EGFP/icre)Uk/Epor+
Genetic
Background		 involves: 129X1/SvJ * BALB/cJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Eportm1.1(EGFP/icre)Uk mutation (2 available); any Epor mutation (27 available)
Slc29a1tm2Msg mutation (0 available); any Slc29a1 mutation (42 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal response to injury ( J:244602 )
• under acute hypoxic conditions, mice exhibit a faster increase in serum adenosine levels than in wild-type mice
decreased susceptibility to injury ( J:244602 )
• under acute hypoxic conditions, mice exhibit reduced tissue hypoxia in the heart, kidney and lung with reduced total cell numbers, albumin and IL6 concentration bronchoalveolar lavage fluid, pulmonary myeloperoxidase activity, and perivascular edema compared with wild-type mice

immune system
decreased interleukin-6 secretion ( J:244602 )
• in the lungs of mice exposed to hypoxic conditions




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory