Phenotypes associated with this allele

• Allele Symbol: Tg(Igh*-Mir125b-1)5Toki
• Allele Name: transgene insertion 5, Toshio Kitamura
• Allele ID: MGI:5317552
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(Igh*-Mir125b-1)5Toki/0	Not Specified	MGI:5317565

Genotype
MGI:5317565

tg1

• Allelic Composition: Tg(Igh*-Mir125b-1)5Toki/0
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

decreased tumor-free survival time ( J:178816 )

• 5 of 13 mice develop lethal lymphoid tumors by 50 weeks of age

neoplasm

increased lymphoma incidence ( J:178816 )

• 5 of 13 mice develop lethal lymphoid tumors by 50 weeks of age

• tumors cells in the bone marrow and peripheral blood exhibit morphologically lymphoblastic features

increased B cell derived lymphoma incidence ( J:178816 )

• in 4 mice

growth/size/body

enlarged spleen ( J:178816 )

hematopoietic system

enlarged spleen ( J:178816 )

decreased hemoglobin content ( J:178816 )

immune system

enlarged spleen ( J:178816 )