Phenotypes associated with this allele

• Allele Symbol: Pax6^tm1.2Xzh
• Allele Name: targeted mutation 1.2, Xin Zhang
• Allele ID: MGI:5317867
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pax6^tm1.2Xzh/Pax6^tm1.2Xzh	B6.129S6-Pax6^tm1.2Xzh	MGI:5317872

Genotype
MGI:5317872

hm1

• Allelic Composition: Pax6^tm1.2Xzh/Pax6^tm1.2Xzh
• Genetic Background: B6.129S6-Pax6^tm1.2Xzh

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

abnormal lens morphology ( J:182769 )

• hypoplastic

• the lens remains attached to the overlying surface ectoderm

• complete lens degeneration at P6

corneal-lenticular stalk ( J:182769 )

abnormal lens fiber morphology ( J:182769 )

• the posterior lens fiber fails to rise up to the anterior lens epithelium

coloboma ( J:182769 )

• the retinal pigmented epithelium of the optic cup presents with an optic coloboma

microphthalmia ( J:182769 )

• conspicuously smaller at E14.5