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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Akt1tm2.1Mbb
targeted mutation 2.1, Morris J Birnbaum
MGI:5317890
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Akt1tm2.1Mbb/Akt1tm2.1Mbb involves: 129S4/SvJae * C57BL/6J * FVB/N MGI:5317895


Genotype
MGI:5317895
hm1
Allelic
Composition
Akt1tm2.1Mbb/Akt1tm2.1Mbb
Genetic
Background
involves: 129S4/SvJae * C57BL/6J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Akt1tm2.1Mbb mutation (0 available); any Akt1 mutation (34 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• mice exhibit increased palmitate oxidation compared with control mice
• in mice fed a high fat diet
• in mice fed a high fat diet
• in mice fed a high fat diet
• at 10 weeks of age in mice fed normal chow
• in mice fed a high fat diet
• at 10 weeks of age in mice fed normal chow
• at 21 to 22 weeks in mice fed normal chow when compared with weight-matched control mice
• at 21 to 22 weeks during the dark cycle when compared with weight-matched control mice
• mice fed a high fat diet exhibit elevated peripheral glucose utilization rate compared with control mice
• mice fed a high fat diet exhibit decreased hepatic glucose production compared with control mice
• in mice fed a high fat diet
• in mice fed a high fat diet
• in mice fed a high fat diet
• in mice fed a high fat diet
• in mice fed a high fat diet
• at 10 weeks of age in mice fed normal chow
• at 21 to 22 weeks in mice fed normal chow when compared with weight-matched control mice

growth/size/body
• in mice fed a high fat diet
• however, body composition at 10 weeks of age on normal chow is normal
• in mice fed a high fat diet
• at 10 weeks of age in mice fed normal chow
• however, body composition is normal
• in mice fed a high fat diet

adipose tissue
• in mice fed a high fat diet
• in mice fed a high fat diet
• however, body composition at 10 weeks of age on normal chow is normal

behavior/neurological
• at 21 to 22 weeks during the dark cycle when compared with weight-matched control mice

liver/biliary system
• in mice fed a high fat diet

cellular
• mice exhibit increased palmitate oxidation compared with control mice





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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory