Analysis Tools
homeostasis/metabolism
|
• in fasting mice
|
|
• at 22 weeks, but not 9 weeks, in male mice when normalized to body weight
|
|
• at 22 weeks, but not 9 weeks, in male mice when normalized to body weight
|
|
• during the dark cycle in male mice at 22 weeks
|
|
• slight in male mice, but not female mice
|
|
• hepatocytes exhibit decreased relative lipid synthesis compared with control cells
|
|
• fatty acid oxidation in the liver of male mice is increased compared to in control mice
|
|
• in fasting mice
|
|
• at 9 weeks, but not 31 weeks, in male mice
|
|
• at 31 weeks in male mice
|
|
• at 31 weeks in male mice
|
liver/biliary system
|
• at 31 weeks in male mice
|
|
• at 31 weeks in male mice
|
|
• induced by age or palmitic acid
• however, mice exhibit normal susceptibility to high fat diet-induced steatosis
|
adipose tissue
|
• at 6, 9 and 20 weeks
|
|
• at 6, 9 and 20 weeks
|
growth/size/body
|
• lean mass and content at 20 weeks in male mice, but not female mice
|
|
• slight in male mice, but not female mice
|
behavior/neurological
|
• slight in female and male mice fed standard chow
• in male mice fed a high fat diet
|
cellular
|
• fatty acid oxidation in the liver of male mice is increased compared to in control mice
|
