All Phenotypes Braf<tm1Tuv> MGI Mouse

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Braf^tm1Tuv
targeted mutation 1, David A Tuveson
MGI:5318063

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Braf^tm1Tuv/Braf^tm1Tuv Gt(ROSA)26Sor^tm1(sb13)Tuv/Gt(ROSA)26Sor⁺ Tg(Tyr-cre/ERT2)13Bos/0 TgTn(sb-T2/Onc)#Dla/0	involves: 129S6/SvEvTac * FVB/N	MGI:5318067

Allelic Composition	Braf^tm1Tuv/Braf^tm1Tuv Gt(ROSA)26Sor^tm1(sb13)Tuv/Gt(ROSA)26Sor⁺ Tg(Tyr-cre/ERT2)13Bos/0 TgTn(sb-T2/Onc)#Dla/0
Genetic Background	involves: 129S6/SvEvTac * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Braf^tm1Tuv mutation (0 available); any Braf mutation (60 available)
Gt(ROSA)26Sor^tm1(sb13)Tuv mutation (0 available); any Gt(ROSA)26Sor mutation (992 available)
TgTn(sb-T2/Onc)#Dla mutation (0 available)
Tg(Tyr-cre/ERT2)13Bos mutation (12 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

increased melanoma incidence ( J:177503 )

• in tamoxifen-treated mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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