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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ppardtm1Yjj
targeted mutation 1, Yan J Jiang
MGI:5318332
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ppardtm1Yjj/Ppardtm1Yjj involves: 129 MGI:5318336


Genotype
MGI:5318336
hm1
Allelic
Composition		 Ppardtm1Yjj/Ppardtm1Yjj
Genetic
Background		 involves: 129
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppardtm1Yjj mutation (0 available); any Ppard mutation (68 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
abnormal epidermis stratum corneum morphology ( J:182124 )
• epidermis less mature than for controls at E16.5 and E17.5
• decreased vacillation and fewer stratum corneum layers at E17.5
abnormal stratum corneum lipid matrix formation ( J:182124 )
• secreted lamellar body contents are not yet organized into elongated lamellar bilayers at E17.5




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory