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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Slamf6tm1Pls
targeted mutation 1, Pamela L Schwartzberg
MGI:5318529
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Sh2d1atm1Pls/Sh2d1atm1Pls
Slamf6tm1Pls/Slamf6tm1Pls
Tg(TcraTcrb)1100Mjb/0 		involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J MGI:5438969
cx2
 		Slamf6tm1Pls/Slamf6tm1Pls
Tg(TcraTcrb)1100Mjb/0 		involves: C57BL/6 * C57BL/6J MGI:5438968


Genotype
MGI:5438969
cx1
Allelic
Composition		 Sh2d1atm1Pls/Sh2d1atm1Pls
Slamf6tm1Pls/Slamf6tm1Pls
Tg(TcraTcrb)1100Mjb/0
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sh2d1atm1Pls mutation (4 available); any Sh2d1a mutation (11 available)
Slamf6tm1Pls mutation (1 available); any Slamf6 mutation (33 available)
Tg(TcraTcrb)1100Mjb mutation (6 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:187431 )
N
• T cells exhibit normal adhesion to wild-type B cells and B cells lacking Slamf6 (Sh2d1atm1Pls)




Genotype
MGI:5438968
cx2
Allelic
Composition		 Slamf6tm1Pls/Slamf6tm1Pls
Tg(TcraTcrb)1100Mjb/0
Genetic
Background		 involves: C57BL/6 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slamf6tm1Pls mutation (1 available); any Slamf6 mutation (33 available)
Tg(TcraTcrb)1100Mjb mutation (6 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:187431 )
N
• T cells exhibit normal adhesion to wild-type B cells and B cells lacking Slamf6 (Sh2d1atm1Pls)




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory