About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Slamf6tm1Pls
targeted mutation 1, Pamela L Schwartzberg
MGI:5318529
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Sh2d1atm1Pls/Sh2d1atm1Pls
Slamf6tm1Pls/Slamf6tm1Pls
Tg(TcraTcrb)1100Mjb/0 		involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J MGI:5438969
cx2
 		Slamf6tm1Pls/Slamf6tm1Pls
Tg(TcraTcrb)1100Mjb/0 		involves: C57BL/6 * C57BL/6J MGI:5438968


Genotype
MGI:5438969
cx1
Allelic
Composition		 Sh2d1atm1Pls/Sh2d1atm1Pls
Slamf6tm1Pls/Slamf6tm1Pls
Tg(TcraTcrb)1100Mjb/0
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sh2d1atm1Pls mutation (4 available); any Sh2d1a mutation (11 available)
Slamf6tm1Pls mutation (1 available); any Slamf6 mutation (33 available)
Tg(TcraTcrb)1100Mjb mutation (6 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:187431 )
N
• T cells exhibit normal adhesion to wild-type B cells and B cells lacking Slamf6 (Sh2d1atm1Pls)




Genotype
MGI:5438968
cx2
Allelic
Composition		 Slamf6tm1Pls/Slamf6tm1Pls
Tg(TcraTcrb)1100Mjb/0
Genetic
Background		 involves: C57BL/6 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slamf6tm1Pls mutation (1 available); any Slamf6 mutation (33 available)
Tg(TcraTcrb)1100Mjb mutation (6 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:187431 )
N
• T cells exhibit normal adhesion to wild-type B cells and B cells lacking Slamf6 (Sh2d1atm1Pls)




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory