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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Odf1tm1Shf
targeted mutation 1, Sigrid Hoyer-Fender
MGI:5319183
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Odf1tm1Shf/Odf1tm1Shf involves: 129S1/Sv * 129X1/SvJ * C57BL/6J MGI:5319184
ht2
 		Odf1tm1Shf/Odf1+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6J MGI:5319185


Genotype
MGI:5319184
hm1
Allelic
Composition		 Odf1tm1Shf/Odf1tm1Shf
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Odf1tm1Shf mutation (0 available); any Odf1 mutation (16 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:183675 )
N
• female mice exhibit normal fertility
abnormal sperm midpiece morphology ( J:183675 )
• disturbed mitochondria organization
oligozoospermia ( J:183675 )
• mature sperm are barely found
asthenozoospermia ( J:183675 )
• sperm exhibit reduced velocities (curvilin-ear, average path and straight line) compared with wild-type cells
• sperm exhibit increased straightness of movement and beat cross frequency compared with wild-type cells

cellular
abnormal sperm midpiece morphology ( J:183675 )
• disturbed mitochondria organization
oligozoospermia ( J:183675 )
• mature sperm are barely found
asthenozoospermia ( J:183675 )
• sperm exhibit reduced velocities (curvilin-ear, average path and straight line) compared with wild-type cells
• sperm exhibit increased straightness of movement and beat cross frequency compared with wild-type cells




Genotype
MGI:5319185
ht2
Allelic
Composition		 Odf1tm1Shf/Odf1+
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Odf1tm1Shf mutation (0 available); any Odf1 mutation (16 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:183675 )
N
• male and female mice exhibit normal fertility
asthenozoospermia ( J:183675 )
• reduced velocity

cellular
asthenozoospermia ( J:183675 )
• reduced velocity




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory