All Phenotypes Fbxo4<tm1Kei> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Fbxo4^tm1Kei
targeted mutation 1, Keiichi I Nakayama
MGI:5319202

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fbxo4^tm1Kei/Fbxo4^tm1Kei	involves: 129P2/OlaHsd * C57BL/6	MGI:5319206
cx2	Fbxo4^tm1Kei/Fbxo4^tm1Kei Fbxw8^tm1Kei/Fbxw8^tm1Kei	involves: 129P2/OlaHsd * C57BL/6	MGI:5319207

Allelic Composition	Fbxo4^tm1Kei/Fbxo4^tm1Kei
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbxo4^tm1Kei mutation (1 available); any Fbxo4 mutation (25 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

normal phenotype

no abnormal phenotype detected ( J:183656 )

• mice are healthy, fertile and phenotypically indistinguishable from wild-type

cellular

cellular phenotype ( J:183656 )

N	• mouse embryonic fibroblasts exhibit normal cyclin D1 degradation and cell cycle progression

Allelic Composition	Fbxo4^tm1Kei/Fbxo4^tm1Kei Fbxw8^tm1Kei/Fbxw8^tm1Kei
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fbxo4^tm1Kei mutation (1 available); any Fbxo4 mutation (25 available)
Fbxw8^tm1Kei mutation (0 available); any Fbxw8 mutation (30 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

cellular phenotype ( J:183656 )

N	• mouse embryonic fibroblasts exhibit normal cyclin D1 degradation and cell cycle progression

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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