All Phenotypes Spink5<m1Btlr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Spink5^m1Btlr
mutation 1, Bruce Beutler
MGI:5319218

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Spink5^m1Btlr/Spink5^m1Btlr	involves: C57BL/6J	MGI:5319225

Allelic Composition	Spink5^m1Btlr/Spink5^m1Btlr
Genetic Background	involves: C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Spink5^m1Btlr mutation (0 available); any Spink5 mutation (58 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

integument

flaky skin ( J:183755 )

scaly skin ( J:183755 )

skin lesions ( J:183755 )

immune system

increased neutrophil cell number ( J:183755 )

• in the spleen and lymph node

hematopoietic system

increased neutrophil cell number ( J:183755 )

• in the spleen and lymph node

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Netherton syndrome		DOID:0050474	OMIM:256500	J:183755

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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