Phenotypes associated with this allele

• Allele Symbol: Ago1^tm1.1Tara
• Allele Name: targeted mutation 1.1, Alexander Tarakhovsky
• Allele ID: MGI:5319524
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Ago1^tm1.1Tara/Ago1^tm1.1Tara Ago2^tm1.1Tara/Ago2^tm1.1Tara Tg(KRT14-cre)1Efu/0	involves: 129P2/OlaHsd	MGI:5319527
cn2	Ago1^tm1.1Tara/Ago1^tm1.1Tara Tg(KRT14-cre)1Efu/0	Not Specified	MGI:5319526

Genotype
MGI:5319527

cn1

• Allelic Composition: Ago1^tm1.1Tara/Ago1^tm1.1Tara; Ago2^tm1.1Tara/Ago2^tm1.1Tara; Tg(KRT14-cre)1Efu/0
• Genetic Background: involves: 129P2/OlaHsd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

integument

epidermal cyst ( J:183622 )

• evaginating hair follicle cysts in the epidermis at P4

sparse hair ( J:183622 )

abnormal hair follicle morphology ( J:183622 )

• evaginating hair follicle cysts in the epidermis at P4

abnormal hair follicle development ( J:183622 )

• shortened and misangled hair follicle growth at P4

hair follicle degeneration ( J:183622 )

thick epidermis ( J:183622 )

• hyperthickened

abnormal skin physiology ( J:183622 )

• apoptotic cells in the basal epidermis

growth/size/body

epidermal cyst ( J:183622 )

• evaginating hair follicle cysts in the epidermis at P4

Genotype
MGI:5319526

cn2

• Allelic Composition: Ago1^tm1.1Tara/Ago1^tm1.1Tara; Tg(KRT14-cre)1Efu/0
• Genetic Background: Not Specified

normal phenotype

no abnormal phenotype detected ( J:183622 )

• no developmental defects are detected