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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ppargc1atm1.1Javi
targeted mutation 1.1, Josep A Villena
MGI:5319541
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Ppargc1atm1.1Javi/Ppargc1atm1.1Javi
Tg(Fabp4-cre)1Rev/0
B6.Cg-Ppargc1atm1.1Javi Tg(Fabp4-cre)1Rev MGI:5319542


Genotype
MGI:5319542
cn1
Allelic
Composition
Ppargc1atm1.1Javi/Ppargc1atm1.1Javi
Tg(Fabp4-cre)1Rev/0
Genetic
Background
B6.Cg-Ppargc1atm1.1Javi Tg(Fabp4-cre)1Rev
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppargc1atm1.1Javi mutation (0 available); any Ppargc1a mutation (48 available)
Tg(Fabp4-cre)1Rev mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
adipose tissue
N
• response to rosiglitazone is similar to controls
• on a high fat diet in a thermoneutral environment
• practically indistinguishable from white adipocytes due to large accumulation of triglycerides in mice on a high fat diet in a thermoneutral environment
• on a high fat diet in a thermoneutral environment
• on a high fat diet in a thermoneutral environment

growth/size/body
• on a high fat diet in a thermoneutral environment
• on a regular chow diet in a thermoneutral environment weigh slightly but not significantly less than littermate controls

liver/biliary system
• slight reduction when on a high fat diet in a thermoneutral environment





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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory