Phenotypes associated with this allele

• Allele Symbol: Ppargc1a^tm1.1Javi
• Allele Name: targeted mutation 1.1, Josep A Villena
• Allele ID: MGI:5319541
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Ppargc1a^tm1.1Javi/Ppargc1a^tm1.1Javi Tg(Fabp4-cre)1Rev/0	B6.Cg-Ppargc1a^tm1.1Javi Tg(Fabp4-cre)1Rev	MGI:5319542

Genotype
MGI:5319542

cn1

• Allelic Composition: Ppargc1a^tm1.1Javi/Ppargc1a^tm1.1Javi; Tg(Fabp4-cre)1Rev/0
• Genetic Background: B6.Cg-Ppargc1a^tm1.1Javi Tg(Fabp4-cre)1Rev

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

adipose tissue phenotype ( J:180984 )

N • response to rosiglitazone is similar to controls

decreased total body fat amount ( J:180984 )

• on a high fat diet in a thermoneutral environment

abnormal brown fat cell morphology ( J:180984 )

• practically indistinguishable from white adipocytes due to large accumulation of triglycerides in mice on a high fat diet in a thermoneutral environment

decreased brown fat cell size ( J:180984 )

• on a high fat diet in a thermoneutral environment

decreased white fat cell size ( J:180984 )

• on a high fat diet in a thermoneutral environment

growth/size/body

decreased body weight ( J:180984 )

• on a high fat diet in a thermoneutral environment

• on a regular chow diet in a thermoneutral environment weigh slightly but not significantly less than littermate controls

liver/biliary system

decreased liver weight ( J:180984 )

• slight reduction when on a high fat diet in a thermoneutral environment