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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Mir21atm1.1Sho
targeted mutation 1.1, Stuart H Orkin
MGI:5319685
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Mir21atm1.1Sho/Mir21atm1.1Sho involves: 129 * C57BL/6 MGI:5319691


Genotype
MGI:5319691
hm1
Allelic
Composition		 Mir21atm1.1Sho/Mir21atm1.1Sho
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mir21atm1.1Sho mutation (0 available); any Mir21a mutation (8 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system
decreased susceptibility to kidney reperfusion injury ( J:183786 )
• decrease in interstitial fibrosis, apoptosis, and tubule injury scores following either unilateral ureteral obstruction or unilateral ischemia reperfusion injury

homeostasis/metabolism
decreased susceptibility to kidney reperfusion injury ( J:183786 )
• decrease in interstitial fibrosis, apoptosis, and tubule injury scores following either unilateral ureteral obstruction or unilateral ischemia reperfusion injury




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory